Caffeine, is a naturally produced medicine from the seeds and leaves of many plants. It is also produced unnaturally to add to certain foods. Caffeine is termed as a medicine because it arouses the central nervous system, causing enhanced alertness. Caffeine gives most people a short-term energy boost and bump up mood. Caffeine is present in tea, many soft drinks, coffee, chocolate, and pain relievers and other over-the-counter medicines. Caffeine tastes very bitter in its natural form. However, most caffeinated drinks undergo processing to cover-up the bitter taste. You may feel caffeine’s effects for up to 6 hours though it is not stored in the body.

Diiodotyrosine, used by the thyroid hormones T4 and T3, Diiodotyrosine may help the thyroid gland to maintain proper function and help preserve lean muscle and supports the thyroid without suppressing TSH levels.

Evodiamine, an alkaloid extract from the Evodiae Fructus plant is known as Evodiamine. It has been referred to as a “hot nature” herb in Chinese literature and medicine. Based on animal studies, Evodiamine increases the natural fat burning rate and stimulates vanilloids for reduction of fat intake. It increases body temperature, influences the adrenal glands to secrete catecholamines and also affects the metabolism of certain drugs. Since it acts like a thermogenic and increases the overall temperature, more fat and calories are burnt due to its intake. This alkaloidal compound has anti obesity effects due to UCP1 (uncoupling protein 1) thermogenesis. In part, evodiamine can prevent diet induced obesity from developing further. It is available in the form of supplement or through Evodiae Fructus plant.

Green Tea Extract increases energy expenditure and affects fat oxidation, which therefore promotes weight loss by increasing the body's metabolism.

Iodotyrosone, which is a form of tyrosine with iodine added.

L-Tyrosine is a proteinogenic polar amino acid, deemed not essential because it can be synthesized by the human body. As a member of the amino acid group that is being used by cells to build proteins, this building block derived its name from the Greek word tyros, which means cheese, because it was discovered in the cheese protein casein. L-Tyrosine can be synthesized from phenylalanine and can be found in foods high on protein, like soy products, poultry, cheese, bananas, dairy products and several seeds, including the sesame seeds. The unique phenol functionality and the occurrence in proteins that belong to the signal transduction process, make this amino acid different. Tyrosine can be converted by tyrosine hydroxylase enzyme into levodopa, a psychoactive drug that is used, among other uses, for clinical treatment of Parkinson’s disease. It is also involved in the synthesis of dopamine, norepinephrine and epinephrine.

Naringin, which is a citrus flavanoid that is found in grapefruit. Naringin is commonly used in energy supplements as it may extend the duration of the effects of caffeine.

Octopamine is a secretion initially discovered in the salivary glands of the Octopus and hence the derivation of the name. it tendso to act as a neurotransmitter, transmitting messages from the neurons to the brain and vice versa. Octopamine has been found to have a tendency to release fat deposits from cells, thus aiding in the loss of weight. It is therefore being used as a slimming agent by most people, even though there is no concrete evidence that it does assist in weight loss, for sure. Octopamine is also believed to increase blood pressure levels when it is in combination with other weight loss stimulating supplements. Although not much is known about Octopamine, a deeper study is being conducted into its uses and effects.

Synephrine is an ingredient that is obtained mainly from the fruit of a small citrus tree, the Citrus aurantium, also known as bitter orange, zhi shi and sour orange. Synephrine is viewed as the safer version of ephedrine, whereby the properties include weight loss, increased fat burning, raised metabolism, as well as boosted energy levels. With such properties, this drug became instantly popular with the weight loss and control circles, but also with the body building community, and is now used in Thermonex EF where fat burning and higher energy level properties are eagerly sought after. Initial research show stimulation of beta-3 receptors, whereby no increased heart rate or blood pressure was observed. It seems that synephrine induces lipolysis and stimulates similarly to caffeine. Some have also observed that synephrine suppresses appetite and increases the metabolic rate.

Yerba Matte contains natural nutrients and antioxidants. It contains 11 polyphenol, which are a group of phytochemicals. Phytochemicals are effective antioxidants and are thought to show anti-cancer effects in mammal by making strong natural defenses of an organism and protecting it against cellular destruction. Yerba Matte leaves also have saponins, which are phytochemicals that help induce the immune system and assist the body in protection against ailment. They have important anti-inflammatory properties. Yerba Matte can also prevent oral cancer. Research has shown it contains 90 percent more nutrients, which boost metabolism, than green tea. Some of the vital antioxidant enzymes in the body are also stimulated by Yerba Matte.